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Table 2 Frequency distribution of VEGF genotypes in different stages of lung cancer

From: Correlation of gene polymorphisms of vascular endothelial growth factor with grade and prognosis of lung cancer

Variables

I

II

III

IV

P value

(n = 108)

(n = 163)

(n = 148)

(n = 39)

–2578C > A (%)

    

0.253

 AA

6 (5.56)

6 (3.68)

11 (7.43)

1 (2.56)

 

 AC

47 (43.52)

59 (36.20)

55 (37.16)

21 (53.85)

 

 CC

55 (50.93)

98 (60.12)

82 (55.41)

17 (43.59)

 

–1154G > A (%)

    

0.042

 AA

1 (0.93)

6 (3.68)

2 (1.35)

1 (2.56)

 

 AG

36 (33.33)

37 (22.70)

40 (27.03)

18 (46.15)

 

 GG

71 (65.74)

120 (73.62)

106 (71.62)

20 (51.28)

 

–460 T > C (%)

    

0.230

 CC

7 (6.48)

6 (3.68)

11 (7.43)

1 (2.56)

 

 CT

47 (43.52)

59 (36.20)

55 (37.16)

21 (53.85)

 

 TT

54 (50.00)

98 (60.12)

82 (55.41)

17 (43.59)

 

+405G > C (%)

    

0.846

 CC

17 (15.74)

35 (21.47)

29 (19.59)

6 (15.38)

 

 CG

58 (53.70)

78 (47.85)

74 (50.00)

23 (58.97)

 

 GG

33 (30.56)

50 (30.67)

45 (30.41)

10 (25.64)