Genotypes | Control | p-value | PCOS | p-value | ||||
rs2479106 | AG | AA | GG | AG | AA | GG | ||
Age (years) | 33.53 ± 0.65 | 32.58 ± 0.49 | 34.40 ± 2.27 | 0.771 | 26.97 ± 0.72 | 26.15 ± 0.60 | 33.00 ± 0.49 | 0.227 |
BMI (kg/m2) | 22.72 ± 0.49 | 21.51 ± 0.26 | 23.41 ± 0.62 | 0.143 | 23.33 ± 0.72 | 23.06 ± 0.54 | 19.96 ± 0.49 | 0.268 |
E2(pg/ml) | 63.06 ± 7.36 | 57.13 ± 4.40 | 42.87 ± 5.23 | 0.436 | 209.61 ± 25.42 | 256.54 ± 16.61 | 102.19 ± 28.39 | 0.184 |
T(nm/l) | 2.93 ± 0.17 | 2.04 ± 0.32 | 1.34 ± 0.32 | 0.147 | 3.99 ± 1.06 | 6.27 ± 2.15 | 2.84 ± 1.05 | 0.727 |
E2/T(ln) | 21.33 ± 1.72 | 72.21 ± 25.10 | 33.11 ± 2.87 | 0.335 | 92.12 ± 12.49 | 93.92 ± 12.68 | 35.98 ± 5.49 | 0.797 |
LH(IU/l) | 5.94 ± 0.64 | 4.79 ± 0.29 | 2.56 ± 0.83 | 0.013* | 15.73 ± 1.31 | 17.11 ± 1.19 | 9.79 ± 1.48 | 0.318 |
FSH(IU/l) | 8.40 ± 0.66 | 7.90 ± 0.31 | 7.00 ± 0.41 | 0.701 | 7.17 ± 0.50 | 6.27 ± 0.33 | 6.78 ± 0.29 | 0.551 |
LH/FSH | 0.78 ± 0.07 | 0.64 ± 0.04 | 0.36 ± 0.11 | 0.007* | 2.99 ± 0.19 | 2.94 ± 0.20 | 1.44 ± 0.12 | 0.068 |
PRL(μg/l) | 4.67 ± 1.35 | 6.31 ± 1.78 | 1.79 ± 0.03 | 0.724 | 14.62 ± 1.59 | 18.21 ± 2.10 | 5.75 ± 1.05 | 0.365 |
rs2768819 | Control | p-value | PCOS | p-value | ||||
AG | AA | GG | Â | AG | AA | GG | ||
Age (years) | 32.6 ± 0.77 | 33.58 ± 0.51 | 34.00 ± 1.00 | 0.935 | 28.63 ± 0.84 | 27.24 ± 0.80 | 22.5 ± 0.65 | 0.269 |
BMI (kg/m2) | 22.7 ± 0.59 | 21.93 ± 0.32 | 21.69 ± 2.79 | 0.465 | 13.52 ± 0.88 | 23.30 ± 0.79 | 19.72 ± 0.86 | 0.678 |
E2(pg/ml) | 62.7 ± 8.65 | 61.36 ± 5.27 | 56.36 ± 25.64 | 0.983 | 197.51 ± 32.63 | 192.59 ± 17.67 | 250.90 ± 30.35 | 0.899 |
T(nm/l) | 2.71 ± 0.33 | 2.09 ± 0.14 | 1.67 ± 0.65 | 0.339 | 2.01 ± 0.15 | 2.55 ± 0.26 | 3.35 ± 0.64 | 0.225 |
E2/T(ln) | 20.5 ± 3.37 | 72.51 ± 10.75 | 32.75 ± 2.51 | 0.241 | 109.08 ± 16.66 | 75.45 ± 15.55 | 84.77 ± 17.94 | 0.917 |
LH(IU/l) | 5.45 ± 0.52 | 5.19 ± 0.34 | 4.58 ± 1.41 | 0.905 | 11.75 ± 1.26 | 16.66 ± 1.61 | 31.70 ± 2.34 | 0.013* |
FSH(IU/l) | 6.59 ± 0.28 | 8.04 ± 0.38 | 8.42 ± 0.44 | 0.057 | 6.58 ± 0.54 | 7.06 ± 0.50 | 6.21 ± 0.54 | 0.779 |
LH/FSH | 0.89 ± 0.09 | 0.68 ± 0.04 | 0.54 ± 0.14 | 0.222 | 1.85 ± 0.16 | 2.44 ± 0.21 | 5.26 ± 0.69 | 0.002* |
PRL(μg/l) | 4.58 ± 2.91 | 7.64 ± 2.18 | 1.80 ± 0.06 | 0.583 | 15.16 ± 1.69 | 19.53 ± 3.71 | 24.43 ± 1.33 | 0.618 |
rs2536951 | Control | p-value | PCOS | p-value | ||||
AG | AA | GG | AG | AA | GG | |||
Age (years) | 33.3 ± 0.99 | 32.61 ± 0.52 | 32.30 ± 0.96 | 0.667 | 27.43 ± 0.68 | 25.98 ± 0.62 | 30.00 ± 2.00 | 0.166 |
BMI (kg/m2) | 22.3 ± 0.61 | 21.71 ± 0.31 | 21.44 ± 0.80 | 0.442 | 23.41 ± 0.79 | 22.99 ± 0.58 | 26.89 ± 3.16 | 0.413 |
E2(pg/ml) | 61.0 ± 6.03 | 56.40 ± 4.51 | 59.45 ± 12.17 | 0.861 | 217.63 ± 29.31 | 247.00 ± 19.28 | 232.68 ± 80.20 | 0.699 |
T(nm/l) | 2.85 ± 0.37 | 2.28 ± 0.36 | 1.09 ± 0.07 | 0.268 | 3.43 ± 0.83 | 4.01 ± 0.48 | 2.12 ± 0.56 | 0.67 |
E2/T(ln) | 20.7 ± 9.80 | 70.70 ± 27.74 | 28.84 ± 1.41 | 0.412 | 93.06 ± 14.93 | 89.39 ± 12.39 | 107.24 ± 9.50 | 0.947 |
LH(IU/l) | 6.19 ± 0.51 | 5.07 ± 0.38 | 5.25 ± 0.70 | 0.284 | 15.74 ± 1.47 | 17.21 ± 1.37 | 12.58 ± 2.02 | 0.739 |
FSH(IU/l) | 8.10 ± 0.59 | 8.14 ± 0.37 | 7.70 ± 0.79 | 0.93 | 6.77 ± 0.51 | 6.36 ± 0.38 | 7.36 ± 0.71 | 0.65 |
LH/FSH | 0.88 ± 0.07 | 0.64 ± 0.04 | 0.72 ± 0.08 | 0.026* | 2.35 ± 0.17 | 2.91 ± 0.21 | 1.75 ± 0.44 | 0.139 |
PRL(μg/l) | 1.73 ± 0.69 | 5.09 ± 1.85 | 3.79 ± 0.63 | 0.98 | 13.15 ± 1.55 | 18.21 ± 2.36 | 18.33 ± 8.65 | 0.358 |
rs2479102 | Control | p-value | PCOS | p-value | ||||
CT | CC | TT | CT | CC | TT | |||
Age (years) | 33.2 ± 0.71 | 33.40 ± 1.06 | 32.80 ± 0.50 | 0.561 | 27.56 ± 0.74 | 23.33 ± 2.60 | 26.60 ± 0.63 | 0.218 |
BMI (kg/m2) | 22.3 ± 0.55 | 22.94 ± 1.05 | 21.64 ± 0.26 | 0.197 | 23.40 ± 0.90 | 20.25 ± 1.88 | 23.48 ± 0.61 | 0.443 |
E2(pg/ml) | 62.4 ± 7.30 | 47.53 ± 4.73 | 59.70 ± 4.79 | 0.525 | 190.30 ± 26.79 | 215.11 ± 31.41 | 240.79 ± 20.58 | 0.35 |
T(nm/l) | 2.75 ± 0.33 | 1.20 ± 0.10 | 2.16 ± 0.29 | 0.191 | 3.24 ± 0.89 | 2.48 ± 0.52 | 3.36 ± 0.45 | 0.915 |
E2/T(ln) | 21.9 ± 3.88 | 24.52 ± 3.66 | 64.40 ± 21.94 | 0.374 | 84.89 ± 12.45 | 89.30 ± 7.27 | 103.02 ± 14.29 | 0.702 |
LH(IU/l) | 5.68 ± 0.58 | 5.06 ± 0.60 | 5.04 ± 0.35 | 0.619 | 14.86 ± 1.61 | 21.22 ± 5.02 | 15.56 ± 1.14 | 0.424 |
FSH(IU/l) | 7.90 ± 0.61 | 9.02 ± 0.90 | 7.86 ± 0.34 | 0.129 | 6.94 ± 0.47 | 6.06 ± 0.30 | 6.32 ± 0.39 | 0.594 |
LH/FSH | 0.80 ± 0.07 | 0.59 ± 0.07 | 0.67 ± 0.04 | 0.243 | 2.13 ± 0.18 | 3.55 ± 0.91 | 2.72 ± 0.22 | 0.092 |
PRL(μg/l) | 4.64 ± 3.35 | 3.79 ± 0.63 | 5.76 ± 1.64 | 0.902 | 13.82 ± 1.57 | 22.26 ± 7.07 | 18.52 ± 2.49 | 0.38 |
rs2670139 | Control | p-value | PCOS | p-value | ||||
CT | CC | TT | CT | CC | TT | |||
Age (years) | 33.2 ± 0.67 | 32.79 ± 1.11 | 32.66 ± 0.51 | 0.807 | 27.59 ± 0.71 | 25.50 ± 2.50 | 26.12 ± 0.60 | 0.318 |
BMI (kg/m2) | 22.20 ± 0.5 | 22.33 ± 1.17 | 21.61 ± 0.25 | 0.458 | 23.40 ± 0.83 | 21.73 ± 2.01 | 23.20 ± 0.55 | 0.857 |
E2(pg/ml) | 57.9 ± 6.98 | 60.14 ± 12.70 | 55.72 ± 3.41 | 0.89 | 214.98 ± 29.90 | 201.58 ± 49.11 | 250.40 ± 17.80 | 0.536 |
T(nm/l) | 2.81 ± 0.31 | 2.15 ± 0.75 | 2.01 ± 0.26 | 0.198 | 3.37 ± 0.85 | 2.46 ± 0.90 | 6.37 ± 2.04 | 0.592 |
E2/T(ln) | 22.0 ± 3.89 | 23.19 ± 7.55 | 66.16 ± 23.76 | 0.371 | 95.37 ± 15.37 | 86.28 ± 11.45 | 91.78 ± 11.84 | 0.979 |
LH(IU/l) | 5.39 ± 1.00 | 4.84 ± 1.49 | 5.03 ± 0.35 | 0.786 | 14.86 ± 1.51 | 22.83 ± 8.24 | 17.63 ± 1.23 | 0.945 |
FSH(IU/l) | 7.65 ± 1.10 | 8.23 ± 2.35 | 8.09 ± 0.36 | 0.129 | 6.57 ± 0.47 | 6.27 ± 0.38 | 6.73 ± 0.36 | 0.272 |
LH/FSH | 0.78 ± 0.14 | 0.63 ± 0.16 | 0.64 ± 0.04 | 0.476 | 2.29 ± 0.19 | 3.73 ± 1.54 | 2.83 ± 0.20 | 0.138 |
PRL(μg/l) | 2.53 ± 0.77 | 1.79 ± 0.04 | 4.63 ± 1.42 | 0.769 | 12.82 ± 1.37 | 16.33 ± 6.65 | 18.17 ± 2.16 | 0.294 |