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Table 2 Univariate and multivariate Cox regression analysis in endometrial cancer patients

From: POLE mutations improve the prognosis of endometrial cancer via regulating cellular metabolism through AMF/AMFR signal transduction

Clinical characteristics

Univariate Cox regression analysis

Multivariate Cox regression analysis

exp (coef)

P

95%CI

exp (coef)

P

95%CI

Histological type

1.661

6.26e-06

1.333 to 2.070

1.064

0.62231

0.831 to 1.363

Histologic grade (G1 vs. G2 + G3)

1.116

0.00076

1.047 to 1.189

1.1

0.00378

1.031 to 1.173

Clinical stage (I + II vs. III + IV)

1.063

5.38e-10

1.043 to 1.084

1.062

2.50e-08

1.040 to 1.085

Age at initial pathologic diagnosis (<  60 vs. ≥ 60)

1.803

0.0158

1.117 to 2.910

1.489

0.12497

0.895 to 2.478

POLE (WT vs. mutated)

0.334

0.00968

0.146 to 0.767

0.256

0.00194

0.108 to 0.606