SNP | Genotype | No Hypertension (N = 4621), N (%) | Hypertension (N = 1418), N (%) | p-value |
---|---|---|---|---|
Cohort A (N = 6039) | ||||
rs7330636 | GG | 555 (85.9) | 989 (89.2) | 0.092 |
GA | 89 (13.8) | 115 (10.4) | ||
AA | 2 (0.3) | 5 (0.5) | ||
rs9590999 | CC | 167 (25.1) | 335 (29.2) | 0.056 |
CT | 354 (53.2) | 545 (47.6) | ||
TT | 144 (21.7) | 266 (23.2) | ||
rs2183057 | AA | 253 (38.0) | 401 (34.9) | 0.026 |
AG | 331 (49.7) | 553 (48.1) | ||
GG | 82 (12.3) | 195 (17.0) | ||
rs4942595 | TT | 168 (25.2) | 339 (29.5) | 0.041 |
TC | 354 (53.1) | 541 (47.1) | ||
CC | 145 (21.7) | 269 (23.4) | ||
rs4531630 | AA | 168 (25.3) | 338 (29.6) | 0.062 |
AG | 344 (51.7) | 584 (51.1) | ||
GG | 153 (23.0) | 221 (12.2) | ||
rs17069883 | AA | 197 (29.5) | 287 (25.0) | 0.041 |
AC | 341 (51.1) | 594 (51.7) | ||
CC | 129 (19.3) | 268 (23.3) | ||
rs4942578 | CC | 258 (38.7) | 431 (37.5) | 0.225 |
CA | 320 (48.0) | 530 (46.1) | ||
AA | 89 (13.3) | 188 (16.4) | ||
Cohort B (N = 7524) | ||||
rs4942578 | CC | 1834 (39.2) | 949 (40.2) | 0.605 |
CA | 2171 (46.5) | 1089 (46.2) | ||
AA | 668 (14.3) | 320 (13.6) | ||
rs985933 | AA | 1526 (32.8) | 781 (33.2) | 0.496 |
AG | 2257 (48.5) | 1154 (49.1) | ||
GG | 875 (18.8) | 414 (17.6) | ||
rs4941573 | TT | 1184 (25.4) | 565 (24.0) | 0.196 |
TC | 2314 (49.6) | 1221 (51.8) | ||
CC | 1172 (25.1) | 571 (24.2) | ||
rs6313 | GG | 1229 (26.3) | 584 (24.8) | 0.153 |
GA | 2301 (49.2) | 1218 (51.7) | ||
AA | 1143 (24.5) | 556 (23.6) | ||
rs1328685 | TT | 4031 (86.3) | 2054 (87.1) | 0.259 |
TC | 611 (13.1) | 295 (12.5) | ||
CC | 31 (0.7) | 9 (0.4) | ||
rs2567675 | TT | 2823 (60.4) | 1483 (62.9) | 0.124 |
TC | 1616 (34.6) | 762 (32.3) | ||
CC | 234 (5.0) | 112 (4.8) |