Fig. 7
From: An analysis of mutational signatures of synonymous mutations across 15 cancer types
Analysis of mutation distribution in protein domains. a Venn diagram showing the number of domain types for the multiple intersections among hotspot mutations, neutral synonymous mutations and non-hotspot mutations. b Bar diagram where the value 100% represents the total number of mutations in the nine protein domains common to hotspot, neutral synonymous and non-hotspot mutations. Blue, salmon and green sections on the bar represent which proportions of the total mutations are hotspot, neutral synonymous and non-hotspot mutations, respectively. PF00001, 7tm_1 domain; PF00383, dCMP_cyt_deam_1 domain; PF02492, cobW domain; PF00012, HSP70 domain; PF00520, Ion_trans domain; PF07679, I-set domain; PF00055, Laminin_N domain; PF03062, MBOAT domain; PF09773, Meckelin domain