Fig. 6

Validation studies of correlation between CNV and differential gene expression on CCLP. a. Boxplots show the relationship of Z score (y-axis) versus copy number value (x-axis, processed by PICNIC) among 1020 cell lines. b. The significant difference between Z scores of copy number amplified genes versus copy number deleted genes. c. Scatter plot shows the distribution of genes based on the frequency of copy number amplification and expression level upregulation (x-axis) and the frequency of copy number deletion and expression level downregulation (y-axis). The color represents the count ratio of copy number deletion and expression level downregulation against copy number amplification and expression level upregulation, blue representing higher ratio of copy number deletion and expression level downregulation, red representing higher ratio of copy number amplification and expression level upregulation. A&U: copy number amplification and expression level upregulation. D&D: copy number deletion and expression level downregulation