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Table 3 The frequency of genotypes and alleles of rs3740051 in patients with PA without recurrence and PA with recurrence

From: SIRT1 (rs3740051) role in pituitary adenoma development

Genotype/allele

Frequency (%)

OR*** (CI) p value

PA without recurrence group, N (%) (n = 112)

PA with recurrence group, N (%) (n = 30)

p value*

Genotype

 G/G

0 (0)

2 (6.7)

 

–

 G/A

20 (17.9)

2 (6.7)

0.022**

0.354 (0.078–1.614) 0.35

 A/A

92 (82.1)

26 (86.7)

 

Reference

Allele

 G

20 (8.9)

6 (9.7)

0.856*

1.124 (0.444–2.843) 0.805

 A

204 (91.1)

56 (90.3)

 

–

  1. PA pituitary adenoma, p value significance level, OR odds ratio, CI confidence interval.
  2. *Pearson’s χ 2 test
  3. **Fisher’s exact test
  4. ***Odds ratios were evaluated under the codominant and additive genetic models
  5. Bold entries have significant values
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BMC Medical Genetics

ISSN: 1471-2350

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