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Table 1 Scale for methodological quality assessment

From: Relationship between the rs2596542 polymorphism in the MICA gene promoter and HBV/HCV infection-induced hepatocellular carcinoma: a meta-analysis

Criteria

Score

1.Representativeness of cases

 1.1 HCC and LC diagnosed according to acknowledged criteria.

2

 1.2 Mentioned the diagnosed criteria but not specifically described.

1

 1.3 Not Mentioned.

0

2.Source of controls

 2.1 Cases and control from the same cohort

1

  2.1.1 Defined HCC-free controls according to clinical, biochemical and serological parameters

2

  2.1.2 Only defined HCC-free controls as CHB or LC but not described

1

 2.2 Not described

0

3.Sample size

 3.1 > 300

2

 3.2100–300

1

 3.3 < 100

0

4.Quality control of genotyping methods

 4.1 Repetition of partial/total tested samples with a different method

2

 4.2 Repetition of partial/total tested samples with the same method

1

 4.3 Not described

0

5.Hardy-Weinberg equilibrium (HWE)

 5.1 Hardy-Weinberg equilibrium in control subjects

1

 5.2 Hardy-Weinberg disequilibrium in control subjects

0