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Table 3 Meta-analysis of the association between the TGF-β1 + 869 T/C gene polymorphism with the risk of acute rejection in renal transplantation

From: Relationship between TGF-β1 + 869 T/C and + 915 G/C gene polymorphism and risk of acute rejection in renal transplantation recipients

Genetic contrasts Groups and subgroups Studies Q test Model selected OR (95% CI) P
P value
T vs C Overall 15 0.30 Fixed 1.01 (0.88, 1.15) 0.93
  Caucasian 9 0.78 Fixed 0.99 (0.84, 1.16) 0.88
Asian 4 0.02 Random 1.03 (0.58, 1.82) 0.93
African 1 Fixed 0.84 (0.52, 1.36) 0.47
TT vs (TC + CC) Overall 17 0.19 Fixed 1.08 (0.89, 1.31) 0.44
  Caucasian 10 0.45 Fixed 1.05 (0.83, 1.33) 0.67
Asian 5 0.03 Random 1.06 (0.47, 2.41) 0.88
African 1 Fixed 0.96 (0.54, 1.73) 0.90
CC vs (TC + TT) Overall 16 0.57 Fixed 1.04 (0.84, 1.30) 0.70
  Caucasian 9 0.89 Fixed 0.99 (0.76, 1.29) 0.95
Asian 4 0.13 Fixed 1.01 (0.62, 1.67) 0.96
African 1 Fixed 1.99 (0.72, 5.51) 0.19