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Table 2 Distribution of genotype and allele frequencies of the ATM rs189037 polymorphism

From: ATM rs189037 (G > A) polymorphism increased the risk of cancer: an updated meta-analysis

 

Genotype distribution

  

Allele frequency

 

Cases, n

Controls, n

 

Cases, %

Controls, %

Author

GG

GA

AA

GG

GA

AA

P HWE

G

A

G

A

Kim

190

316

105

195

306

113

0.7130

56.96

43.04

56.68

43.32

Wang

428

580

224

474

567

191

0.3210

58.28

41.72

61.49

38.51

Bau

181

277

162

239

285

96

0.4704

51.53

48.47

61.53

38.47

Lo

238

345

145

239

354

124

0.7173

56.39

43.61

58.02

41.98

Wang

89

128

49

106

119

41

0.4295

57.52

42.48

62.22

37.78

Xu

375a

215

606a

277

Hsia

118

176

64

255

339

122

0.6068

57.54

42.46

59.29

40.71

Zhao

140

186

58

125

203

56

0.0697

60.68

39.32

58.98

41.02

Damiola

13

32

23

35

106

60

0.3121

42.65

57.35

43.78

56.22

Gu

90

196

69

102

189

69

0.2638

52.96

47.04

54.58

45.42

Liu

217

435

200

264

434

154

0.2927

51.00

49.00

56.46

43.54

Shen

148

240

99

152

272

92

0.1186

55.03

44.97

55.81

44.19

Song

134

211

83

56

84

42

0.3352

55.96

44.04

53.85

46.15

Yue

166

262

96

196

258

64

0.1371

56.68

43.32

62.74

37.26

Wang

336

543

227

362

491

191

0.2797

54.93

45.07

58.19

41.81

  1. Abbreviation: PHWE represents the P value of Hardy-Weinberg equilibrium test in the genotype distribution of controls
  2. arepresents the number of GG + GA