Skip to main content

Table 4 Allele Counts and Minor Allele Frequencies

From: Discovery of rare ancestry-specific variants in the fetal genome that confer risk of preterm premature rupture of membranes (PPROM) and preterm birth

rs Number

Term

PPROM

MAC/TA

Homo

Het

MAF

MAC/TA

Homo

Het

MAF

p Value (nominal)

rs5743490 Combineda

1/751

0

1

0.0013

10/694

1

8

0 .0144

(p < 0.004)

rs74754826 Combineda

1/751

0

1

0.0013

8/694

1

8

0.0115

(p < 0.015)

rs115687886 Combined

10(9)/254

1

8(7)

0.035

20(19)/318

0

20(19)

0.060

(p > 0.05)

  1. MAC/TA Minor allele count/total alleles, MAF Minor allele frequency, Homo Homozygous, Het Heterozygous
  2. (9) = rs115687886 nonsense mutations subtracting out those with an adjacent rs1466636131 minor allele
  3. a Data derived from the present study and Modi et al. [9]