From: Potential role for nectin-4 in the pathogenesis of pre-eclampsia: a molecular genetic study
 | Normotensive Pregnancy | Severe pre-eclampsia | P Value |
---|---|---|---|
N = 25 | N = 22 | ||
Maternal age (y) | 29.4 ± 5.8a | 30.2 ± 3.6 | n.s. |
Gestational age (wks) | 33.2 ± 5.1 | 32.9 ± 3.8 | n.s. |
Parity (n) | 0.71 ± 0.76 | 0.22 ± 0.42 | P < 0.05 |
Systolic BP (mmHg) | 113.0 ± 10.0 | 169.6 ± 14.5 | P < 0.05 |
Diastolic BP (mmHg) | 66.8 ± 9.8 | 105.9 ± 13.9 | P < 0.05 |
Proteinuriab | 0 (0%) | 22 (100%) | P < 0.05 |
Body mass index (BMI)c | 22.3 ± 4.6 | 22.3 ± 7.5 | n.s. |
Placental weight (g) | 480.0 ± 244.1 | 312.9 ± 126.7 | P < 0.05 |
Birth weight (g) | 1984.9 ± 905.7 | 1585.5 ± 722.6 | P < 0.05 |
Birth weight coefficient | 1.012 ± 0.129 | 0.742 ± 0.215 | P < 0.05 |
Hb (g/dl) | 10.9 ± 0.9 | 12.0 ± 1.9 | n.s. |
Platelet count (× 104/ul) | 25.2 ± 3.8 | 15.4 ± 8.2 | p < 0.05 |
GOT (IU/l) | 18.3 ± 7.5 | 39.5 ± 31.7 | p < 0.05 |
GPT (IU/l) | 15.4 ± 16.4 | 25.7 ± 15.8 | n.s. |
LDH (IU/l) | 206.8 ± 36.1 | 333.4 ± 98.1 | p < 0.05 |