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Table 1 Characteristics of the subjects with normotensive pregnancies and severe pre-eclampsia

From: Potential role for nectin-4 in the pathogenesis of pre-eclampsia: a molecular genetic study

 

Normotensive Pregnancy

Severe pre-eclampsia

P Value

N = 25

N = 22

Maternal age (y)

29.4 ± 5.8a

30.2 ± 3.6

n.s.

Gestational age (wks)

33.2 ± 5.1

32.9 ± 3.8

n.s.

Parity (n)

0.71 ± 0.76

0.22 ± 0.42

P < 0.05

Systolic BP (mmHg)

113.0 ± 10.0

169.6 ± 14.5

P < 0.05

Diastolic BP (mmHg)

66.8 ± 9.8

105.9 ± 13.9

P < 0.05

Proteinuriab

0 (0%)

22 (100%)

P < 0.05

Body mass index (BMI)c

22.3 ± 4.6

22.3 ± 7.5

n.s.

Placental weight (g)

480.0 ± 244.1

312.9 ± 126.7

P < 0.05

Birth weight (g)

1984.9 ± 905.7

1585.5 ± 722.6

P < 0.05

Birth weight coefficient

1.012 ± 0.129

0.742 ± 0.215

P < 0.05

Hb (g/dl)

10.9 ± 0.9

12.0 ± 1.9

n.s.

Platelet count (× 104/ul)

25.2 ± 3.8

15.4 ± 8.2

p < 0.05

GOT (IU/l)

18.3 ± 7.5

39.5 ± 31.7

p < 0.05

GPT (IU/l)

15.4 ± 16.4

25.7 ± 15.8

n.s.

LDH (IU/l)

206.8 ± 36.1

333.4 ± 98.1

p < 0.05

  1. Hb Hemoglobin, GOT Glutamate oxaloacetate transaminase, GPT Glutamate pyruvate transaminase, LDH Lactate dehydrogenase
  2. aData are given as the mean ± standard deviation (SD)
  3. b≥2 g in a 24 h collection
  4. cpre-pregnancy