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Table 3 c.103G > T (p.Val35Leu) and c.1694C > T (p.Pro564Leu) Variants in aSAH subtypes

From: Factor XIII polymorphism and risk of aneurysmal subarachnoid haemorrhage in a south Indian population

Variable

Case

Val/Val (p)

Val/Leu (p)

Leu/Leu (p)

Val

Leu

Val Vs Leu (p)

Pro/Pro (p)

Pro/Leu (p)

Leu/Leu (p)

Pro

Leu

Pro Vs Leu (p)

Total

200

180

18

2

378

22

 

92

74

34

258

142

 

Site of Aneurysm

 ACOM

86

75(0.86)

11(0.38)

0(0.62)

161

11

0.67

42 (0.79)

26 (0.44)

18(0.51)

110

62

0.90

 PCOM

12

11(0.96)

1(0.94)

0(0.45)

23

1

0.78

4 (0.58)

7(0.35)

1(0.50)

15

9

0.84

 ICA

36

32(0.96)

3(0.90)

1(0.40)

67

5

0.62

16(0.91)

16(0.57)

4(0.44)

48

24

0.72

 MCA

37

36(0.76)

1(0.24)

0(0.96)

73

1

0.16

14 (0.56)

17(0.50)

6(0.92)

45

29

0.54

 Multiple

22

20(0.97)

2(0.98)

0(0.71)

42

2

0.79

13 (0.50)

6(0.52)

3(0.73)

32

12

0.27

 Basilar top

7

6(0.93)

0(0.82)

1(0.03)

12

2

0.18

3 (0.91)

2(0.75)

2(0.52)

8

6

0.57

Size of aneurysm

 Small(< 15 mm)

159

141(0.92)

17(0.62)

1(0.70)

299

19

0.78

76(0.83)

55(0.74)

28(0.89)

207

111

0.86

 Large(15-25 mm)

37

36(0.76)

0

1(0.42)

72

2

0.32

15(0.70)

17(0.50)

5(0.65)

47

27

0.87

 Giant(> 25 mm)

4

3(0.81)

1(0.37)

0

7

1

0.41

1(0.58)

2 (0.73)

1(0.73)

4

4

0.40

WFNS Grade

 Grade I

91

82(0.99)

8(0.95)

1(0.93)

172

10

0.99

38(0.67)

31(0.73)

22(0.24)

107

75

0.18

 Grade II

42

36(0.84)

5(0.59)

1(0.48)

77

7

0.32

21(0.77)

17(0.77)

4(0.29)

59

25

0.31

 Grade III

51

47(0.91)

4(0.81)

0

98

4

0.52

26(0.71)

20(0.40)

5(0.27)

72

30

 

 Grade IV

16

15(0.91)

1(0.73)

0

31

1

0.57

7(0.91)

6(0.97)

3(0.88)

20

12

0.82

  Male

77

73(0.78)

4(0.33)

0

150

4

0.15

39(0.68)

26(0.72)

12(0.81)

104

50

0.50

  Female

123

107(0.14)

14(0.53)

2(0.62)

228

18

0.35

53(0.75)

48(0.80)

22(0.86)

154

92

0.62

 Hypertension (+)

37

32(0.33)

5(0.44)

0

69

5

0.66

14(0.56)

18(0.38)

5(0.65)

46

28

0.70

 Diabetes mellitus (+)

71

65(0.93)

5(0.63)

1(0.78)

136

7

0.78

34(0.86)

25(0.85)

12(0.98)

93

49

0.83

 Alcohol (+)

57

53(0.88)

4(0.66)

0

110

4

0.39

29(0.69)

18(0.60)

10(0.93)

76

38

0.66

 Smoking (+)

58

54(0.87)

4(0.64)

0

112

4

0.37

31(0.55)

19(0.68)

8(0.61)

81

35

0.28

  1. p-value < 0.05 are given in bold