Skip to main content
Fig. 4 | BMC Medical Genetics

Fig. 4

From: Muscle-specific regulation of right ventricular transcriptional responses to chronic hypoxia-induced hypertrophy by the muscle ring finger-1 (MuRF1) ubiquitin ligase in mice

Fig. 4

Functional annotation of differentially expressed genes in MuRF1 Tg + right ventricles after three weeks CH exposure. a. Identification of ZIC1 protein binding sites based on binding sites in 5 of the differentially expressed genes in MuRF1 Tg + heart (Jakmip3, Cyp2b13, Gucd1, Kansl1l, Rab3gap1). The number of genes in dataset and enrichment (sites/sequence ratio) for each transcription factor is calculated to the right. b. STRING analysis of the top 27 genes increased (> 3-fold) and top 18 genes decreased (<− 3-fold) listed in Fig. 3b. c. Functional annotation of differentially expressed MuRF1 Tg + right ventricle by STRING analysis

Back to article page

BMC Medical Genetics

ISSN: 1471-2350

Contact us