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Fig. 2 | BMC Medical Genetics

Fig. 2

From: Muscle-specific regulation of right ventricular transcriptional responses to chronic hypoxia-induced hypertrophy by the muscle ring finger-1 (MuRF1) ubiquitin ligase in mice

Fig. 2

Functional annotation of differentially expressed genes in MuRF1−/− right ventricle after three weeks CH exposure. a. Hypercluster analysis of differentially expressed MuRF1−/− genes in the right ventricle after hypoxia challenge using the DAVID v6.8 Functional Annotation Bioinformatics database. Differentially expressed gene symbols are on the left, functional categories along the top (database source in parentheses). The cluster fold enrichment is color-coded (key in lower right). b. Reverse transcriptase quantitative PCR analysis of MuRF1−/− hearts of differentially expressed genes MuRF1, Atp2b2, and Elovl7 mRNA in the right ventricle

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BMC Medical Genetics

ISSN: 1471-2350

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