Fig. 2
From: A Chinese family affected by lynch syndrome caused by MLH1 mutation
Clinical examination results. a and b Abdominal computed tomography (CT) scan of the proband (III7) revealed an obstructing mass located in the hepatic flexure of the colon (arrow). a, axial and b, coronal. c and d A space-occupying lesion in colon by colonoscopy in III7. e HE staining demonstrates moderately-differentiated colon adenocarcinoma with glandular architecture, nuclear atypia and dysregulated cell proliferation. f immunochemistry stain of MLH1. g and h Abdominal computer tomography of III5 showed a obstructing mass in the same location of colon as the proband (III7) (arrow). g, axial view. h, coronal view. i and j Colonoscopy of IV8. i Before the preventative treatment, ileocecal mucosa showed sign of chronic inflammation with erosion, lymphoid hyperplasia and mild atypical hyperplasia of glandular epithelium. j After oral administration of aspirin for 6 months, same site of ileocecal mucosa showed improved appearance overall