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Table 3 Associations of haplotypes with prediabetes and type 2 diabetes (T2DM)

From: UCP2 and UCP3 variants and gene-environment interaction associated with prediabetes and T2DM in a rural population: a case control study in China

Haplotype

Frequency (%)

OR

p

aORa

pa

Prediabetes

 rs643064-rs660339

  CG

57.8

0.91 (0.74,1.12)

0.393

0.91 (0.74,1.12)

0.372

  CA

12.0

0.95 (0.70,1.29)

0.736

0.98 (0.72,1.34)

0.907

  TA

30.0

1.14 (0.91,1.43)

0.241

1.13 (0.90,1.42)

0.289

 rs7930460-rs647126-rs1685356

  AAC

18.3

1.04 (0.80,1.35)

0.795

1.02 (0.78,1.33)

0.865

  AAT

38.5

0.96 (0.78,1.18)

0.721

0.98 (0.79,1.21)

0.842

  AGC

11.8

0.85 (0.62,1.15)

0.281

0.85 (0.63,1.16)

0.311

  GGC

31.4

1.11 (0.89,1.38)

0.346

1.10 (0.88,1.37)

0.422

T2DM

 rs643064-rs660339

  CG

58.5

0.94 (0.77,1.15)

0.542

0.94 (0.76,1.16)

0.551

  CA

11.5

0.90 (0.66,1.23)

0.514

0.90 (0.66,1.24)

0.533

  TA

30.0

1.14 (0.92,1.43)

0.234

1.15 (0.91,1.44)

0.246

 rs7930460-rs647126-rs1685356

  AAC

20.3

1.17 (0.91,1.51)

0.220

1.14 (0.87,1.48)

0.337

  AAT

38.8

0.98 (0.80,1.20)

0.820

1.01 (0.81,1.24)

0.951

  AGC

11.4

0.82 (0.60,1.11)

0.197

0.79 (0.58,1.09)

0.148

 GGC

29.5

1.01 (0.81,1.26)

0.900

1.02 (0.81,1.28)

0.880

  1. OR odds ratio, T2DM type 2 diabetes
  2. aAdjusted for age, sex, regular exercise, income, excessive drinking, smoking, hypertension and overweight