Involvement of polymorphisms of the nerve growth factor and its receptor encoding genes in the etiopathogenesis of ischemic stroke

Table 2 HWE and MAFs of the selected SNPs in the studied groups and in major population

Gene SNP ID	Minor allele	MAF (frequency/number)			HWE (P)
Gene SNP ID	Minor allele	IS patients	Controls	1000 Genomes	IS patients	Controls
NGF rs6330	T	0.406/138	0.205/82	0.248/1239	0.95	0.12
NGF rs6330	T	0.406/138	P = 0.06		0.95	0.12
NGF rs4839435	A	0.344/117	0.333/133	0.176/880	0.98	0.165
NGF rs4839435	A	0.344/117	P < 0.0001		0.98	0.165
NGFR rs11466155	T	0.282/96	0.263/102	0.229/1151	0.5	0.6
NGFR rs11466155	T	0.282/96	P = 0.25		0.5	0.6
NGFR rs2072446	T	0.378/125	0.293/117	0.053/264	0.99	0.094
NGFR rs2072446	T	0.378/125	P < 0.0001		0.99	0.094
NGFR rs734194	G	0.1/34	0.273/109	0.106/533	0.72	0.26
NGFR rs734194	G	0.1/34	P < 0.0001		0.72	0.26

ISSN: 1471-2350