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Table 4 P-values of comparisons of S100B SNPs on allele and genotype level in the pooled population

From: S100B polymorphisms are associated with age of onset of Parkinson’s disease

  rs9722 rs2239574 rs881827 rs9984765 rs1051169
p-Valuea allele *4.1 × 10 −6 0.448 0.043 0.007 0.028
p-Valuea genotype *5.0 × 10 −5 0.233 0.131 0.018 0.049
p-Valueb allele *0.003 0.912 0.132 0.016 0.038
p-Valueb genotype 0.015 0.731 0.289 0.034 0.079
ORc 2.9 (1.8–4.7) 1.1 (0.8–1.6) 1.4 (1.0–2.0) 1.6 (1.1–2.1) 1.4 (1.0–1.9)
  1. aEarly onset PD (≤50 years) compared to late onset PD (> 50 years). bEarly onset PD compared to controls. cOR (95% confidence interval) for early onset PD compared to controls. Significant (p < 0.05) results are shown in bold. With Bonferroni correction for multiple testing (analyses of 5 SNPs and 3 comparisons; controls versus all PD patients, controls versus early onset PD and early onset versus late onset PD) significant (p < 0.0033) results are shown by *. P-values were calculated from Chis-square test and ORs were calculated using logistic regression