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Table 1 Baseline characteristics of the cohort

From: Association of common genetic variants related to atrial fibrillation and the risk of ventricular fibrillation in the setting of first ST-elevation myocardial infarction

Variables Cases (n = 257) Controls (n = 537) P value
Female sex, No. (%) 35 (14) 131 (25) 0.001
Median Age at index infarction, y (IQR) 60 (53–68) 61 (52–66) 0.100
Cardiovascular risk profile
Body mass index (kg/m2), (IQR) 27.2 (25–29) 26.7 (24–29) 0.400
Smoking (pack year), (IQR) 25 (5–41) 25 (6–42) 0.200
Smoking, No. (%)
 Never 38 (16) 108 (20) 0.300
 Past 69 (28) 133 (25)
 Current 136 (56) 290 (55)
Alcohol per week, (unit*, IQR) 6 (1–15) 3 (0–9) <0.001
Alcohol units per week (categorized), No. (%)
 Non-drinkers 46 (19) 143 (27) <0.001
 Normal (1–7) 90 (38) 242 (46)
 Moderate High (8–14) 41 (17) 70 (13)
 High (>15) 60 (26) 73 (14)
Diabetes, No. (%) 30 (12) 47 (9) 0.200
Hypertension, No. (%) 102 (41) 184 (35) 0.070
COPD, No. (%) 12 (5) 30 (6) 0.700
Hypercholesterolemia, No. (%) 97 (39) 165 (31) 0.023
Stroke, No. (%) 18 (7) 26 (5) 0.200
Atrial fibrillation, No. (%) 16 (7) 10 (2) 0.006
Depression, No. (%) 28 (11) 65 (12) 0.700
Epilepsy, No. (%) 4 (2) 5 (1) 0.500
Family History, No. (%)
 Sudden death 94 (40%) 128 (25%) <0.001
 Myocardial infarction 90 (40%) 195 (38%) 0.600
 Stroke 36 (16%) 75 (15%) 0.600
Medication before MI, No. (%)
β-blockers 20 (8) 43 (8) 0.900
Statins 55 (22) 65 (12) <0.001
ACE/ARB blockers 50 (21) 90 (17) 0.200
Aspirin 28 (12) 40 (8) 0.060
  1. IQR: interquartile range; unit of alcohol =12 g (1 drink); COPD: chronic obstructive pulmonary disease; MI: myocardial infarction; ACE/ARB: angiotensin-converting-enzyme inhibitor/ angiotensin II receptor blocker