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Table 2 Distribution of the AGT, AGTR1, and ACE genotypes and the frequency of alleles in the study population

From: Renin-angiotensin system gene polymorphisms and high blood pressure in Lithuanian children and adolescents

Characteristics Boys Girls
HBP NBP HBP NBP
AGT, M235 T genotypes, n (%)
 MM 45 (27.3) 49 (27.1) 28 (27.2) 65 (26.7)
 MT 82 (49.7) 77 (42.5) 57 (55.3) 125 (51.2)
 TT 38 (23.0) 55 (30.4) 18 (17.5) 54 (22.1)
  χ2 = 2.70, p = 0.259 χ2 = 0.99, p = 0.607
AGT, M235 T alleles, frequency
 M 0.52 0.48 0.55 0.52
 T 0.48 0.52 0.45 0.48
  χ2 = 0.99, p = 0.321 χ2 = 0.39, p = 0.531
AGTR1, A1166C genotypes, n (%)
 AA 87 (52.4) 85 (47.2) 59 (56.2) 123 (50.2)
 AC 67 (40.4) 77 (42.8) 39 (37.1) 107 (43.7)
 CC 12 (7.2) 18 (10.0) 7 (6.7) 15 (6.1)
  χ2 = 1.35, p = 0.508 χ2 = 1.29, p = 0.524
AGTR1, A1166C alleles, frequency
 A 0.73 0.69 0.75 0.72
 C 0.27 0.31 0.25 0.28
  χ2 = 1.32, p = 0.251 χ2 = 0.55, p = 0.450
ACE, ID genotypes, n (%)
 II 34 (20.6) 58 (31.6) 25 (24.0) 65 (26.4)
 ID 94 (57.0) 79 (42.9) 55 (52.9) 126 (51.2)
 DD 37 (22.4) 47 (25.5) 24 (23.1) 55 (22.4)
  χ2 = 7.74, p = 0.021 χ2 = 0.22, p = 0.897
ACE, ID alleles, frequency
 I 0.49 0.53 0.50 0.52
 D 0.51 0.47 0.50 0.48
  χ2 = 1.06, p = 0.304 χ2 = 0.14, p = 0.707
  1. Comparisons between groups were performed by applying the χ2 test
  2. Abbreviations: NBP normal blood pressure, HBP high blood pressure, AGT angiotensinogen, AGTR1 angiotensin II receptor 1, ACE angiotensin-converting enzyme