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Table 3 association between FTO (rs9939609) polymorphism and Clinical characteristics of subjects

From: The (FTO) gene polymorphism is associated with metabolic syndrome risk in Egyptian females: a case- control study

Characteristics

FTO (rs9939609) Genotypes

P

TT(n = 67)

AT(n = 104)

AA(n = 26)

 

Age, years, mean ± S.D

46.3 ± 8.6

44.02 ± 9.8

45.65 ± 10.7

0.29 a

BMI, Kg/m2, mean ± S.D

31 ± 8

31.37 ± 8.2

33.1 ± 7.2

0.51a

Waist (cm),mean ± S.D

103.2 ± 20.2

103.3 ± 20.1

106.8 ± 16.1

0.69a

TC (mg/dl), mean ± S.D

178.3 ± 33.1

172.4 ± 36.2

163.4 ± 38

0.18 a

TAG (mg/dl), mean ± S.D

148.3 ± 73.8

138.6 ± 71.9

136 ± 58

0.62 a

HDL-C (mg/dl), mean ± S.D

43.2 ± 10.7

42.2 ± 8

37 ± 8.5

0.01 a

LDL-C (mg/dl), mean ± S.D

105.4 ± 29.7

102.5 ± 32.7

99.3 ± 27.7

0.67 a

FPG (mg/dl), median(min-max)

108(69–323)

100.5(60–361)

138.5(76–350)

0.2 b

FSI(μIU/mL), median(min-max)

10.5(2.4–30)

9.73(1–30.3)

12.2(2.9–29.3)

0.59 b

HOMA-IR,median(min-max)

3.1 (0.6–23.9)

2.4 (0.2–20.45)

3.6 (1.29–20.46)

0.28 b

QUICKI, mean ± S.D

0.33 ± 0.042

0.34 ± 0.06

0.32 ± 0.034

0.11 a

AST(IU/mL), median(min-max)

15(4–53)

12.5(4–60)

17(8–58)

0.19 b

ALT(IU/mL), median(min-max)

14(4–60)

11(4–57)

15.5(6–58)

0.02 b

  1. BMI Body mass index, WC Waist circumference, T.C Total cholesterol, TAG Triacylglycerol, HDL-C High density lipoprotein-cholesterol, LDL-C Low density lipoprotein-cholesterol, FPG Fasting plasma glucose, FSI Fasting serum insulin
  2. aone way ANOVA test, two-sided p value >0.05 non-significant
  3. b Kruskal-Wallis test, two-sided p value >0.05 non-significant
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BMC Medical Genetics

ISSN: 1471-2350

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