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Table 4 Multivariable models of waist circumference, sum of skin fold thickness and total body fat adjusted for sex, age, BMI, BMI2, total energy intake, smoking, type of work, shift work, comorbidities

From: Allelic variants in vitamin D receptor gene are associated with adiposity measures in the central-European population

 

SNP

Genotypes

Waist circumference [cm]

Sum of skin fold thickness [cm]

Total body fat [%]

β estimate

p

β estimate

p

β estimate

p

Var. 1

ApaI

AA

(ref)

(ref)

(ref)

AC

−1.68

(−2.88;-0.48)

0.006

−0.45

(−4.19;3.28)

0.811

0.35

(−0.27;0.96)

0.270

CC

−0.69

(−2.09;0.71)

0.333

0.08

(−4.70;4.86)

0.974

0.56

(−0.16;1.28)

0.130

EcoRV

AA

(ref)

(ref)

(ref)

AG

0.66

(−0.40;1.72)

0.220

−1.12

(−4.76;2.52)

0.545

−0.26

(−0.84;0.33)

0.389

GG

0.73

(−0.65;2.11)

0.301

−5.21

(−9.62;-0.80)

0.021

−0.51

(−1.26;0.23)

0.176

FokI

TT

(ref)

(ref)

(ref)

TC

0.19

(−0.84;1.21)

0.720

−0.66

(−3.81;2.49)

0.680

0.01

(−0.58;0.60)

0.974

CC

0.01

(−1.28;1.30)

0.987

0.79

(−3.60;5.18)

0.723

−0.21

(−0.95;0.53)

0.584

Var. 2

BsmI

CC

(ref)

(ref)

(ref)

CT

−0.50

(−1.50;0.49)

0.319

−0.42

(−3.81;2.96)

0.805

−0.02

(−0.56;0.53)

0.957

TT

0.70

(−0.82;2.23)

0.364

−1.77

(−6.68;3.15)

0.478

−1.17

(−1.95;-0.38)

0.004

EcoRV

AA

(ref)

(ref)

(ref)

AG

0.70

(−0.36;1.76)

0.196

−1.10

(−4.75;2.56)

0.554

−0.25

(−0.84;0.33)

0.392

GG

0.67

(−0.72;2.07)

0.342

−5.17

(−9.59;-0.75)

0.022

−0.47

(−1.21;0.28)

0.218

FokI

TT

(ref)

(ref)

(ref)

TC

0.20

(−0.84;1.23)

0.710

−0.73

(−3.86;2.39)

0.645

−0.04

(−0.63;0.54)

0.883

CC

−0.03

(−1.32;1.25)

0.959

0.71

(−3.67;5.08)

0.750

−0.26

(−0.99;0.48)

0.492

Var. 3

TaqI

AA

(ref)

(ref)

(ref)

AG

−1.08

(−2.14;-0.02)

0.046

0.46

(−3.12;4.03)

0.801

−0.30

(−0.86;0.26)

0.292

GG

−0.35

(−1.86;1.16)

0.649

−1.07

(−5.76;3.61)

0.651

−0.87

(−1.67;-0.07)

0.033

EcoRV

AA

(ref)

(ref)

(ref)

AG

0.65

(−0.41;1.71)

0.229

−1.07

(−4.69;2.55)

0.559

−0.25

(−0.84;0.33)

0.398

GG

0.67

(−0.73;2.07)

0.344

−5.14

(−9.54;-0.74)

0.022

−0.51

(−1.25;0.24)

0.180

FokI

TT

(ref)

(ref)

(ref)

TC

0.18

(−0.85;1.21)

0.735

−0.75

(−3.88;2.38)

0.638

−0.03

(−0.61;0.56)

0.931

CC

0.00

(−1.29;1.29)

0.999

0.67

(−3.74;5.09)

0.763

−0.20

(−0.94;0.53)

0.588

  1. Var: combinations of three genotypes in the given model: Var 1: ApaI-EcoRV-FokI; Var 2: BsmI-EcoRV-FokI; Var 3: TaqI-EcoRV-FokI in the model