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Fig. 1 | BMC Medical Genetics

Fig. 1

From: Case report of unexpected gastrointestinal involvement in type 1 Gaucher disease: comparison of eliglustat tartrate treatment and enzyme replacement therapy

Fig. 1

Gross and pathological findings of the duodenal mucosa in Cases 1 and 2. Gaucher cell infiltration presenting with multiple yellowish nodular lesions in the upper gastrointestinal (GI) endoscopy at baseline (a), persistent lesions 6 months after a high dose of enzyme (b), slightly improving multiple nodular lesions at 6 months (c), and grossly improving at 12 months (d) after eliglustat tartrate administration in Case 1. Persistent multiple nodular lesions in Case 2 at baseline (e, f), and 12 months (g, h) after ERT. Gaucher cell infiltration in the duodenal mucosa at baseline (H&E, ×40, ×200, ×400) (i, j, k). Gaucher cells are strongly positivity for CD68, which is a special stain for macrophages and Gaucher cells (CD68, ×40) (l)

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BMC Medical Genetics

ISSN: 1471-2350

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