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Table 2 Clinical profile of the cohort

From: Screening of WT1 mutations in exon 8 and 9 in children with steroid resistant nephrotic syndrome from a single centre and establishment of a rapid screening assay using high-resolution melting analysis in a clinical setting

Characteristic

 

Patients (n)

100 (50females/50 males)

Ethnic background (Southern region/Northern region/Eastern region; %)

90/9/1

Consanguinity (%)

12

Onset of NS (congenital/infantile/childhood primary SRNS/Unknown; %)

4/4/80/12

Age at diagnosisa (years; Median, IQR)

2.5 (1.2–6.2)

Edema

74%

Proteinuria (yes/unavailable; %)

81/19

Hematuria (Yes/No/unavailable; %)

13/52/35

Hypertension (yes/no/unavailable)

35/45/20

Serum albumin (g/l; Median, Range)

1.7 (1.2–2.3)

Histopathology subtype (%)

 

 Minimal change disease

37

 Focal segmental glomerulosclerosis

21

 Mesangial hypercellularity

12

 Others

9

 Not performed

21

Renal outcome (%)

 

 Remission

4

 Persistent relapse

62

 Chronic Kidney disease Stage II-IV

22

 End-stage renal disease

12

  1. aincomplete data on 11/100 patients