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Table 2 Clinical and genetic information for sample sets used for association analysis with BMI, T2D and gout

From: Lack of direct evidence for natural selection at the candidate thrifty gene locus, PPARGC1A

 

obs missing (n)

NZ Caucasian

obs missing (n)

NZ Māori

obs missing (n)

CI Māori

obs missing (n)

Samoan

obs missing (n)

Tongan

Individuals

-

1007

-

322

-

136

-

223

-

114

Gout (%)

-

64.3

9

42.5

1

52.2

3

64.6

-

64.0

Diabetes (%)

10

11.5

11

42.8

4

26.5

6

14.3

3

18.4

Mean age (range)

-

59.7 (18–94)

1

50.9 (17–82)

-

52.4 (18–88)

-

44.3 (17–71)

-

42.8 (18–79)

Sex (% male)

2

76.1

1

56.8

-

61.8

2

82.1

-

86.8

Mean BMI Gly/Gly (range)

6

29.1 (17.8–61.6)

1

32.3 (23.0–42.2)

2

35.9 (33.1–40.7)

-

37.2 (26.0–62.5)

-

34.5 (26.3–44.2)

Mean BMI Gly/Ser (range)

9

29.3 (18.8–60.7)

3

33.0 (21.3–61.7)

-

34.5 (21.4–66.7)

3

37.7 (22.2–93.4)

-

36.5 (26.6–48.5)

Mean BMI Ser/Ser (range)

-

29.7 (19.3–62.9)

3

34.2 (18.4–65.8)

1

36.5 (23.0–80.0)

1

36.7 (20.5–70.3)

1

36.8 (25.8–70.6)

Allele frequency rs8192678 Ser allele (Gout; Control)

2

0.346 (0.332; 0.371)

2

0.801 (0.803; 0.798)

-

0.805 (0.782; 0.836)

-

0.688 (0.698; 0.671)

-

0.636 (0.651; 0.61)

Allele frequency rs8192678 Ser allele (Diabetes; Control)

2

0.346 (0.366; 0.345)

2

0.801 (0.788; 0.807)

-

0.805 (0.847; 0.786)

-

0.688 (0.703; 0.689)

-

0.636 (0.667; 0.622)

  1. BMI body mass index, Gly glycine, Ser serine