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Fig. 1 | BMC Medical Genetics

Fig. 1

From: CCM3/SERPINI1 bidirectional promoter variants in patients with cerebral cavernous malformations: a molecular and functional study

Fig. 1

Transcription activity analysis of CCM3/SERPINI1 haplotypes of the c.-639 T > C and c.-591 T > C polymorphisms. The transcription activity was measured using the Dual-Luciferase Reporter Assay System in U373 MG (human, Caucasian, glioblastoma-astrocytoma) cells. Luciferase activities are representative of at least three independent experiments, with each construct tested in triplicate per experiment. *p < 0.01; **p > 0.05

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BMC Medical Genetics

ISSN: 1471-2350

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