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Table 4 Multivariate Cox proportional hazard regression illustrating risk of cardiovascular mortality in the population divided into the two genders, and with a follow-up period of 80 months

From: PDGF-D gene polymorphism is associated with increased cardiovascular mortality in elderly men

Variables

Females

Males

Hazard ratio

95 % confidence interval

P-value

Hazard ratio

95 % confidence interval

P-value

Age

1.16

0.99–1.37

0.07

1.16

1.04–1.28

0.006

Diabetes

2.66

0.92–7.65

0.07

0.98

0.51–1.89

0.95

Hypertension

1.47

0.40–5.36

0.56

1.39

0.69–2.83

0.36

IHD

2.18

0.64–7.42

0.21

0.79

0.37–1.70

0.54

BMI

1.06

0.96–1.17

0.22

0.89

0.80–0.99

0.04

Hb < 120 g/L

2.12

0.71–6.35

0.18

1.35

0.43–4.23

0.61

eGFR < 60 mL/min

3.06

0.78–12.00

0.11

0.82

0.41–1.64

0.58

ACEI/ARB

0.96

0.34–2.71

0.93

1.04

0.50–2.15

0.92

Beta blockers

0.91

0.32–2.55

0.86

1.07

0.53–2.19

0.84

EF < 40 %

1.08

0.20–5.85

0.93

2.38

0.98–5.77

0.05

s-Cholesterol

0.91

0.58–1.41

0.66

0.96

0.70–1.33

0.83

PDGF-D G/A or A/A

0.36

0.12–1.05

0.06

2.72

1.39–5.32

0.003

  1. Notes: ACEI/ARB ACE-inhibitors, or Angiotensin receptor blockers, BMI body mass index, EF ejection fraction based on echocardiography, IHD ischemic heart disease
  2. Note: eGFR was based on the MDRD formula