Acyl-CoA synthetase long-chain 5 genotype is associated with body composition changes in response to lifestyle interventions in postmenopausal women with overweight and obesity: a genetic association study on cohorts Montréal-Ottawa New Emerging Team, and Complications Associated with Obesity

Table 8 Regression analysis studying lifestyle intervention effect in CT/TT vs CC women with obesity

Multiple regression model	Dependent variable	Number of subjects (n)	Parameter estimate	Standard error	Variable p-value	r² model	r² adjusted model	Model p-value
1	∆ BMI	87	−2.14	1.05	0.045	0.129	0.087	0.022
2	∆ Lean Mass	85	0.49	1.07	0.645	0.151	0.086	0.041
3	∆ Fat Mass	85	−5.13	1.97	0.011	0.212	0.151	0.004
4	∆ % Lean Mass	85	3.12	1.19	0.010	0.257	0.189	0.001
5	∆ % Fat Mass	85	−3.30	1.30	0.013	0.252	0.194	0.001
6	∆ Visceral fat	85	−9.53	3.47	0.007	0.214	0.164	0.002
7	∆ Muscle attenuation	87	1.20	0.72	0.098	0.177	0.126	0.007

* Multiple linear regression analysis was conducted. Parameter estimate of independent variable = Xt was studied. Physiological factors (dependent variables) were studied while adjusting for confounding factors independent for each model (Table 2). Analysis was conducted on MONET and CAO studies combined

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