Acyl-CoA synthetase long-chain 5 genotype is associated with body composition changes in response to lifestyle interventions in postmenopausal women with overweight and obesity: a genetic association study on cohorts Montréal-Ottawa New Emerging Team, and Complications Associated with Obesity

Table 3 Pre- and post-intervention anthropometric variable values from MONET and CAO women with overweight or obesity

Biological factor observed	MONET study			CAO study			P-value
Biological factor observed	Mean	Std. Dev.	Size (n)	Mean	Std. Dev	Size (n)	P-value
Age (yrs)	57.9	4.87	106	56.5	4.11	29	0.155
Height (m)	1.61	0.06	106	1.63	0.08	29	0.068
Pre-Intervention
BMI (kg/m²)	32.4	4.74	106	34.3	3.56	29	0.041
Lean Mass (kg)	42.8	6.66	106	45.6	7.44	29	0.054
Fat Mass (kg)	38.5	9.57	106	43.6	9.21	29	0.011
Lean Mass (%)	51.5	4.59	106	49.8	3.62	29	0.072
Fat Mass (%)	45.6	4.70	106	47.2	3.73	29	0.084
Visceral Fat (cm²)	185	54.7	105	200	56.5	29	0.197
Thigh Muscle Attenuation (HU)	48.8	3.34	106	48.2	3.04	29	0.326
Post-Intervention
BMI (kg/m²)	30.3	4.76	105	32.3	3.69	29	0.042
Lean Mass (kg)	41.9	5.70	104	43.6	6.56	29	0.168
Fat Mass (kg)	33.9	10.1	104	40.1	9.51	29	0.004
Lean Mass (%)	54.2	5.36	104	50.9	4.56	29	0.003
Fat Mass (%)	42.6	5.52	104	45.9	4.76	29	0.004
Visceral Fat (cm²)	162	57.7	102	177	51.3	29	0.215
Thigh Muscle Attenuation (HU)	48.6	3.56	105	48.1	3.27	29	0.542

* Results are from unpaired t-tests. Test was conducted on data from all subjects whose blood samples were available for study

ISSN: 1471-2350