Fig. 1

Histological analysis of control and DMD patient. Muscle sections were stained with Hematoxylin-Eosin (a-b). Normal muscle was compared to dystrophic one (a). The dystrophic muscle presented marked variability in fiber size, fiber splitting, scattered necrotic and regenerating fibers, and prominent endomysial and perimysial fibrosis (b). Muscle sections cut from normal (c) and dystrophic muscle were stained with dystrophin antibodies (d) in green. Nuclei were stained with DAPI