Tracking of the origin of recurrent mutations of the BRCA1 and BRCA2 genes in the North-East of Italy and improved mutation analysis strategy

Table 5 Haplotype analyses in the BRCA1 c.676delT carrier families

	D17S588	D17S806	D17S902	D17S855 (BRCA1) ^a	D17S1328	D17S800	D17S250
BR128	154-156	168-170	149-149	149–153	247–247	170–174	153–159
BR328	154–154	170–172	149–153	147–149	247–247	166–174	149–159
BR384	148–154	170–178	145–149	149–155	247–249	174–174	149–159
BR392	154–159	168–170	149–153	145–149	247–247	174–174	145–155
BR573	154–156	162–176	149–153	147–149	247–251	170–174	149–153
BR613	138–154	170–172	149–153	143–149	247–247	170–174	149–149
BR704	140–154	170–176	145–149	147–149	247–247	170–176	145–155
BR977	154–156	170–174	149–157	149–153	247–247	170–174	151–153
BR1091	148–154	170–170	149–157	149–151	247–247	170–174	151–161

Alleles segregating with the mutation inside each family are represented in bold type. The 149–149–247 shared haplotype is underlined
^a D17S855 is located into the BRCA1 locus

ISSN: 1471-2350