Region # | Trait | Consecutive Significantly Associated Haplotype Windows (global P < 0.05) | |||||||
---|---|---|---|---|---|---|---|---|---|
 |  | Haplotype Windows # | Chr12 Positiona | The Composited Variants in the Region, 5′ to 3′ Direction | Most Relevant Haplotype | ||||
(Location) | |||||||||
 |  |  | Start (5′) | End (3′) | SNP Nameb-SNP IDc/Chr12 Positiona | Major/Minor Alleles | Haplotype # | Sequence | β (Min-Max) |
1 | HDL-C | 44 | 125300551 | 125299542 | p48969-rs2343394 | C/T | h44.3 | CCWGCGG | 0.4910–1.0491 |
 | 45 | (intron 2) | (exon 3) | p49537-rs7305310 | C/T | h45.2 |  |  | |
 | 46 |  |  | p49570delC-rs145376237 | W/D | h46.2 |  |  | |
 | 47 |  |  | p49690-rs4765615 | G/A | hap.base47 |  |  | |
 |  |  |  | p49759-rs146272788 | C/T | hap.base44 | CCWACGG | −0.4701 | |
 |  |  |  | p49978-rs5891 (p.Val135Ile) | G/A | hap.base45 |  |  | |
 |  |  |  | p50024-rs368880622 | G/T | hap.base46 |  |  | |
 |  |  |  |  |  | h47.1 |  |  | |
2 | ApoA-I | 47 | 125299830 | 125299369 | p49690-rs4765615 | G/A | h47.1 | ACGGTT | (−0.8907)–3.3792 |
 | 48 | (intron 2) | (intron 3) | p49759-rs146272788 | C/T | h48.1 |  |  | |
 | 49 |  |  | p49978-rs5891 (p.Val135Ile) | G/A | h49.1 |  |  | |
 |  |  |  | p50024-rs368880622 | G/T |  |  |  | |
 |  |  |  | p50118-rs58710319 | C/T |  |  |  | |
 |  |  |  | p50151-rs2278986 | T/C |  |  |  | |
3 | ApoA-I | 70 | 125294893 | 125292516 | p54627-chr12_125294893 | G/C | h70.2 | GCGTAG | 2.0304–2.1103 |
 | 71 | (intron 5) | (intron 6) | p54856-chr12_125294664d | C/T | h71.3 |  |  | |
 | 72 |  |  | p55923-rs838900 | G/A | h72.3 |  |  | |
 |  |  |  | p55963-rs7134858 | C/T |  |  |  | |
 |  |  |  | p56845-rs838902 | A/G |  |  |  | |
 |  |  |  | p57004-rs187562853 | G/A |  |  |  | |
4 | ApoA-I | 78 | 125291928 | 125286037 | p57592-rs838903 | G/A | h78.5 | GTTTCGCTG | 4.7307–5.5715 |
 | 79 | (intron 7) | (intron 7) | p58514-rs838905 | T/C | h79.6 |  |  | |
 | 80 |  |  | p58664-rs865716 | A/T | h80.6 |  |  | |
 | 81 |  |  | p60255-rs3782287 | C/T | hap.base81 |  |  | |
 | 82 |  |  | p61872-rs838909 | C/T | hap.base82 |  |  | |
 | 83 |  |  | p62140-rs838910 | G/T | hap.base83 |  |  | |
 |  |  |  | p62409-rs838911 | C/T | h78.2 | GTACCTCTG | 0.6384–3.8641 | |
 |  |  |  | p62615-rs7138386 | T/C | h79.2 |  |  | |
 |  |  |  | p63483-rs838912 | G/A | hap.base80 |  |  | |
 |  |  |  |  |  | h81.3 |  |  | |
 |  |  |  |  |  | h82.2 |  |  | |
 |  |  |  |  |  | h83.4 |  |  | |
5 | ApoA-I | 95 | 125277653 | 125272763 | p71867-rs7954022 | C/T | h95.5 | CGTTCT | 4.2363-4.7525 |
 | 96 | (intron 9) | (intron 9) | p72197-rs838861 | A/G | h96.5 |  |  | |
 | 97 |  |  | p72777-rs838862 | C/T | h97.4 |  |  | |
 |  |  |  | p75766-rs838866 | T/C |  |  |  | |
 |  |  |  | p75778-rs7301120 | C/T |  |  |  | |
 |  |  |  | p76757-rs9919713 | A/T |  |  |  | |
6* | ApoA-I | 109 | 125271118 | 125269475 | p78402-rs838898 | G/A | h109.6 | GCCTGCA | (−3.3720)─(−1.8104) |
 | 110 | (intron 10) | (intron 11) | p78430-rs838897 | C/G | h110.6 |  |  | |
 | 111 |  |  | p78747-rs2293440 | T/C | h111.2 |  |  | |
 | 112 |  |  | p78791-rs75289200 | T/C | h112.3 |  |  | |
 |  |  |  | p79721-rs838896 | G/C |  |  |  | |
 |  |  |  | p79828-rs838895 | C/G |  |  |  | |
 |  |  |  | p80045-rs838893 | G/A |  |  |  | |
7* | HDL-C | 111 | 125270773 | 125267501 | p78747-rs2293440 | T/C | h111.4 | TTGGAGC | 0.3755–2.3949 |
 | 112 | (intron 11) | (intron 11) | p78791-rs75289200 | T/C | h112.2 |  |  | |
 | 113 |  |  | p79721-rs838896 | G/C | h113.1 |  |  | |
 | 114 |  |  | p79828-rs838895 | C/G | h114.1 |  |  | |
 |  |  |  | p80045-rs838893 | G/A |  |  |  | |
 |  |  |  | p81863-rs185445624 | G/A |  |  |  | |
 |  |  |  | p82019-rs838890 | C/T |  |  |  | |
8 | HDL-C | 117 | 125267501 | 125267086 | p82019-rs838890 | C/T | h117.2 | TCGGC | (−1.0134)–(−0.9657) |
 | 118 | (intron 11) | (intron 12) | p82264-rs141545424 (p.Gly501Gly)d | C/A | h118.2 |  |  | |
 |  |  |  | p82340-rs77483223 | G/A |  |  |  | |
 |  |  |  | p82369-rs75446635 | G/A |  |  |  | |
 |  |  |  | p82434-rs838889 | T/C |  |  |  | |
9 | HDL-C | 123 | 125265636 | 125262553 | p83884-rs701106 | C/T | h123.4 | CCCTGA | (−1.180)–(−0.2329) |
 | 124 | (intron 12) | (exon 13-3′ UTR) | p86245-rs188375019 | C/T | h124.2 |  |  | |
 | 125 |  |  | p86276-rs747155 | C/T | h125.2 |  |  | |
 |  |  |  | p86316-rs701104 | G/T |  |  |  | |
 |  |  |  | p86481-rs701103 (p.Gly499Arg, isoform 2) | G/A |  |  |  | |
 |  |  |  | p86967-rs187492239 | A/G |  |  |  |