Table 1 A summary of data collected and corresponding outcome measures
From: Genetics, sleep and memory: a recall-by-genotype study of ZNF804A variants and sleep neurophysiology
| Â | Data source | Outcome measures |
|---|---|---|
Primary outcome measures | Polysomnography | Sleep variables derived from scored recordings, e.g. total sleep time (TST), sleep onset latency (SOL), sleep efficiency (SE), wake after sleep onset (WASO) |
Time spent in each sleep stage; S1, S2, Slow wave sleep (SWS) and rapid eye movement sleep (REM) | ||
Spectral composition of EEG data (delta, theta, alpha, sigma and beta frequency bands) | ||
Motor sequence task | Number of correct sequences pre- and post-sleep | |
Percentage improvement | ||
Reaction time pre- and post-sleep | ||
Secondary outcome measures | Actigraphy | Sleep/Wake estimates e.g. sleep period, sleep efficiency, total sleep time. |
Non-parametric circadian rhythm analysis (NPCA) e.g. 10 most active hours (M10), 5 least active hours (L5) | ||
Daily activity levels | ||
Sleep diary | Detailed information about rest/activity routine (to aid interpretation of actigraphy) | |
Pittsburgh Sleep Quality Index | Sleep quality (over previous month) | |
Bristol Sleep Profile | Assessment for sleep disorders (eligibility) | |
St Mary’s Hospital Sleep Questionnaire | Sleep quality, latency, continuity, satisfaction etc. (study nights) | |
Leeds Sleep Evaluation Questionnaire | Total Score and individual components; Getting to sleep, quality of sleep, awake following sleep, behaviours following awakening (study nights) | |
| Â | Stanford Sleepiness Scale | Assessment of alertness prior to MST |