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Fig. 3 | BMC Medical Genetics

Fig. 3

From: SNP55, a new functional polymorphism of MDM2-P2 promoter, contributes to allele-specific expression of MDM2 in endometrial cancers

Fig. 3

ASE of MDM2 mRNA analyzed by PLACE-SSCP method. Allelic ratio in genomic DNA and relative allele-specific expression ratio in cDNA from the same samples that analyzed by the post-labeling followed by automated capillary electrophoresis under single-strand conformation polymorphism conditions (PLACE-SSCP) method with either marker single nucleotide polymorphism (SNP) rs1690916 (a), (b); or marker SNP rs937283 (c), (d); in cancer-free endometria (a), (c); and endometrial cancer (b), (d). The y-axis represents the fluorescent signal ratio from each allele (SNP rs1690916: G-peak height/A-peak height; SNP rs937283: A-peak height/A-peak height). Dark grey bars indicate the corrected genomic allelic ratios and light grey bars indicate the corrected cDNA allelic ratios

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BMC Medical Genetics

ISSN: 1471-2350

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