Fig. 2

Columnar scatter plots of the expression of the six genes in osteoarthritis (OA) hip cartilage stratified by genotype at the association SNP rs9350591. Gene expression for (a) COL12A1, (b) TMEM30A, (c) MYO6, (d) SENP6, (e) FILIP1 and (f) COX7A2 was normalised to that of the housekeepers 18S, GAPDH and HPRT1. Each dot represents one donor and n is the number of donors studied in each group. CC is the major allele homozygote genotype at the association SNP rs9350591, whilst T carriers are those that are either heterozygote (CT) or minor allele homozygote (TT) at the SNP. The horizontal lines represent the mean and the error bars represent the standard error of the mean (SEM). Statistical significance was assessed using the Mann–Whitney U test and is not corrected for multiple testing