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Fig. 1 | BMC Medical Genetics

Fig. 1

From: Functional characterisation of the osteoarthritis susceptibility locus at chromosome 6q14.1 marked by the polymorphism rs9350591

Fig. 1

Columnar scatter plots of the expression of the six genes in osteoarthritis (OA) and non-OA hip cartilage. Non-OA hip cartilage was obtained from patients who had undergone a total hip replacement due to a neck-of-femur (NOF) fracture. Gene expression for (a) COL12A1, (b) TMEM30A, (c) MYO6, (d) SENP6, (e) FILIP1 and (f) COX7A2 was normalised to that of the housekeepers 18S, GAPDH and HPRT1. Each dot represents one donor and n is the number of donors studied in each group. The horizontal lines represent the mean and the error bars represent the standard error of the mean (SEM). Statistical significance was assessed using the Mann–Whitney U test and is not corrected for multiple testing. * p < 0.05; ** p < 0.01

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