From: Adjusting heterogeneous ascertainment bias for genetic association analysis with extended families
 | n proband | Statistic | N | |||||
---|---|---|---|---|---|---|---|---|
100 | 300 | 600 | 900 | 1200 | 1400 | |||
0.01 | 1 | WL | 0.027 | 0.062 | 0.129 | 0.219 | 0.293 | 0.369 |
FQLS 1 | 0.029 | 0.064 | 0.122 | 0.220 | 0.304 | 0.372 | ||
FQLS 2 | 0.029 | 0.059 | 0.129 | 0.230 | 0.306 | 0.385 | ||
2 | WL | 0.033 | 0.076 | 0.165 | 0.295 | 0.415 | 0.456 | |
FQLS 1 | 0.036 | 0.073 | 0.166 | 0.309 | 0.418 | 0.461 | ||
FQLS 2 | 0.035 | 0.076 | 0.178 | 0.312 | 0.422 | 0.465 | ||
3 | WL | 0.040 | 0.103 | 0.257 | 0.398 | 0.519 | 0.609 | |
FQLS 1 | 0.039 | 0.112 | 0.257 | 0.404 | 0.526 | 0.623 | ||
FQLS 2 | 0.036 | 0.110 | 0.253 | 0.407 | 0.527 | 0.621 | ||
4 | WL | 0.041 | 0.127 | 0.297 | 0.497 | 0.626 | 0.720 | |
FQLS 1 | 0.044 | 0.129 | 0.307 | 0.502 | 0.626 | 0.719 | ||
FQLS 2 | 0.046 | 0.126 | 0.307 | 0.493 | 0.637 | 0.726 | ||
0.001 | 1 | WL | 0.005 | 0.012 | 0.038 | 0.075 | 0.113 | 0.153 |
FQLS 1 | 0.005 | 0.012 | 0.038 | 0.076 | 0.115 | 0.157 | ||
FQLS 2 | 0.003 | 0.010 | 0.038 | 0.076 | 0.106 | 0.163 | ||
2 | WL | 0.006 | 0.019 | 0.060 | 0.098 | 0.193 | 0.224 | |
FQLS 1 | 0.007 | 0.018 | 0.059 | 0.099 | 0.199 | 0.217 | ||
FQLS 2 | 0.006 | 0.019 | 0.064 | 0.100 | 0.197 | 0.219 | ||
3 | WL | 0.004 | 0.018 | 0.086 | 0.164 | 0.267 | 0.337 | |
FQLS 1 | 0.007 | 0.020 | 0.091 | 0.162 | 0.275 | 0.333 | ||
FQLS 2 | 0.008 | 0.023 | 0.087 | 0.165 | 0.275 | 0.348 | ||
4 | WL | 0.010 | 0.029 | 0.116 | 0.231 | 0.309 | 0.451 | |
FQLS 1 | 0.009 | 0.029 | 0.116 | 0.228 | 0.370 | 0.449 | ||
FQLS 2 | 0.009 | 0.031 | 0.118 | 0.233 | 0.363 | 0.459 |