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Fig. 1 | BMC Medical Genetics

Fig. 1

From: Evaluation of an association between plasma total homocysteine and schizophrenia by a Mendelian randomization analysis

Fig. 1

A meta-analysis of genetic association studies between the MTHFR C677T polymorphism and schizophrenia. Thirty six case–control studies were used for the meta-analysis (N = 25,599). The pooled OR per T allele of the MTHFR C677T polymorphism on schizophrenia risk was 1.13 (95 % CI = 1.06–1.22; p = 5.9 x 10−4) in the random-effects model with significant heterogeneity among studies (I2 = 66.1 %; p < 0.05)

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