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Table 1 In- and exclusion of couples

From: Determining the genome-wide kinship coefficient seems unhelpful in distinguishing consanguineous couples with a high versus low risk for adverse reproductive outcome

Population

 

Case couples

Case individuals

Control couples

Control individuals

TUN

Considered eligible

50

 

102

 
 

Reliable pedigree and suitable sample:

50

 

52

 
 

Blood

 

100

  
 

Saliva

   

104

 

Genotype

    
 

Remaining after DNA quality control

50

 

52

 
 

Remaining after data quality control

47

 

49

 

SAU

Considered eligible

14

 

14

 
 

Reliable pedigree and suitable sample:

13

 

14

 
 

Blood

    
 

Saliva

    
 

Genotype

 

26

 

28

 

Remaining after DNA quality control

13

 

14

 
 

Remaining after data quality control

11

 

12

 

TUR

Considered eligible

9

 

12

 
 

Reliable pedigree and suitable sample:

9

 

12

 
 

Blood

 

4

  
 

Saliva

 

14

 

24

 

Genotype

    
 

Remaining after DNA quality control

7

 

10

 
 

Remaining after data quality control

6

 

10

 

MOR

Considered eligible

4

 

3

 
 

Reliable pedigree and suitable sample:

3

 

2

 
 

Blood

    
 

Saliva

 

6

 

4

 

Genotype

    
 

Remaining after DNA quality control

3

 

2

 
 

Remaining after data quality control

3

 

1

 

JOR

Considered eligible

7

 

7

 
 

Reliable pedigree and suitable sample:

2

 

3

 
 

Blood

    
 

Saliva

 

4

 

6

 

Genotype

    
 

Remaining after DNA quality control

2

 

3

 
 

Remaining after data quality control

2

 

3

 

PAK

Considered eligible

16

 

16

 
 

Reliable pedigree and suitable sample:

1

 

1

 
 

Blood

    
 

Saliva

 

2

 

2

 

Genotype

    
 

Remaining after DNA quality control

1

 

1

 
 

Remaining after data quality control

1

 

1

 

NLD

Considered eligible

1

 

2

 
 

Reliable pedigree and suitable sample:

1

 

1

 
 

Blood

    
 

Saliva

 

2

 

2

 

Genotype

    
 

Remaining after DNA quality control

1

 

1

 
 

Remaining after data quality control

1

 

1

 

AFG

Considered eligible

1

   
 

Reliable pedigree and suitable sample:

1

   
 

Blood

    
 

Saliva

 

2

  
 

Genotype

    
 

Remaining after DNA quality control

1

   
 

Remaining after data quality control

1

   

IRQ

Considered eligible

2

 

2

 
 

Reliable pedigree and suitable sample:

1

 

1

 
 

Blood

    
 

Saliva

 

2

 

2

 

Genotype

    
 

Remaining after DNA quality control

0

 

1

 
 

Remaining after data quality control

0

 

1

 

IRN

Considered eligible

1

   
 

Reliable pedigree and suitable sample:

1

   
 

Blood

 

2

  
 

Saliva

    
 

Genotype

    
 

Remaining after DNA quality control

1

   
 

Remaining after data quality control

1

   

TOTAL

Considered eligible

105

 

158

 
 

Reliable pedigree and suitable sample

82

 

86

 
 

Remaining after DNA quality control

79

 

84

 
 

Remaining after data quality control

73

 

78

 
  1. TUN Tunisia, SAU Saudi Arabia, TUR Turkey, MOR Morocco, JOR Jordan, PAK Pakistan, NLD the Netherlands, AFG Afghanistan, IRQ Iraq, IRN Iran)