From: Molecular and clinical study of a cohort of 110 Algerian patients with autosomal recessive ataxia
Features (68 patients) | Number of patients (%) or value |
---|---|
Age of onset (mean, range-years) | 11.1 ± 5.97 SD (birth-35) |
Cerebellar syndrome | 68 (100Â %) |
Onset sign | |
 Gait ataxia | 47 (69.12 %) |
 Gait ataxia, frequent falls | 7 (10.29 %) |
 Gait ataxia, muscle weakness | 6 (8.82 %) |
 Gait ataxia, dysarthria | 3 (4.41 %) |
 Gait ataxia, head tremor | 1 (1.47 %) |
 Head tremor | 1 (1.47 %) |
 Head tremor, dysarthria | 1 (1.47 %) |
 Psychomotor retardation | 2 (2.94 %) |
Dysarthria | 59 (86.76Â %) |
Nystagmus | 37 (54.41Â %) |
Visual acuity decline | 7 (10.29Â %) |
Spasticity | 11 (16.17Â %) |
Babinski sign | 22 (32.35Â %) |
Dysmophric signs | |
 Scoliosis | 11 (16.17 %) |
 Pes cavus | 20 (29.41 %) |
 Scoliosis, pes cavus | 21 (30.88 %) |
 Scoliosis, flat feet | 3 (4.41 %) |
 Pes cavus, cranio-facial dysmorphy | 1 (1.47 %) |
 None | 12 (17.64 %) |
Cognitive impairment | 6 (8.82Â %) |
Cardiomyopathy | 7 (10.3Â %) |
Epilepsy (epileptic seizures) | 3 (4.41Â %) |
Oculomotor apraxia | 5 (7.35Â %) |
Hypoacusia | 6 (8.82Â %) |
Head tremor | 10 (14.7Â %) |