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Table 1 Characteristics of participants included in the analysis of the effects of aspirin and UGT1A6 genotype on gene expression in colonic epithelium and stroma

From: Tissue-specific patterns of gene expression in the epithelium and stroma of normal colon in healthy individuals in an aspirin intervention trial

 

UGT1A6*1/*1

UGT1A6*2/*2

 

Men n = 9

Women n = 11

Men n = 9

Women n = 13

Age, years (SD)

30.0 (4.65)

30.9 (5.8)

30.2 (5.6)

29.7 (7.8)

Height, cm (SD)

180.9 (5.6)

168.5 (7.2)

179.0 (7.8)

163.2 (8.0)

Weight, kg (SD)

83.6 (8.4)

69.0 (12.0)

88.2 (26.5)

71.3 (15.5)

BMI, kg/m2 (SD)

25.6 (2.6)

24.2 (3.2)

27.5 (7.8)

26.7 (5.2)

Minority, n (%)

2 (22.2)

3 (27.3)

3 (33.3)

2 (15.4)

Race n (%)

    

 Caucasian

6 (66.7)

6 (54.6)

6 (66.7)

11 (84.6)

 Asian

1 (11.1)

1 (9.1)

2 (22.2)

1 (7.7)

 African-American

0

1 (9.1)

0

0

 Other

2 (22.2)

3 (27.2)

1 (11.1)

1 (7.7)

Family history of CRC, n (%)

0 (0.0)

1 (9.1)

1 (11.1)

0 (0.0)

Take supplements, n (%)

3 (33.3)

2 (18.2)

4 (44.4)

6 (46.2)

Ever smoked n (%)

1 (11.1)

3 (27.3)

1 (11.1)

1 (7.7)

Energy, kcal/d (SD)

1495 (373)

1468 (474)

1770 (459)

1505 (361)

Fruit, servings/d (SD)

1.3 (1.0)

1.9 (0.9)

2.5 (1.8)

2.9 (2.3)

Vegetables, servings/d (SD)

1.5 (1.2)

2.3 (1.2)

1.7 (1.0)

2.6 (2.1)

Caffeine mg/d (SD)

68 (92)

76 (60)

125 (147)

118 (71)

Calcium mg/d (SD)

926 (508)

760 (373)

782 (267)

773 (406)

Fat g/d (SD)

57 (20)

56 (20)

67 (29)

46 (20)

Dietary fiber, g/d

15.9 (8.3)

15.5 (5.6)

19.2 (9.0)

20.4 (8.4)

  1. Abbreviations: CRC, colorectal cancer; SD, standard deviation.
  2. Asterisks are used as part of the specific classification of the UGT1A6 genotype.