Table 3 The allelic distributions of GATA4 polymorphism among patients and controls
From: c.620C>T mutation in GATA4 is associated with congenital heart disease in South India
dbSNP | Control allele (n = 400) | ASD allele (n = 66) | VSD allele (n = 64) | TOF allele (n = 64) | Control vs. ASD | Control vs. VSD | Control vs. TOF | |||
|---|---|---|---|---|---|---|---|---|---|---|
p-value | OR (95% CI) | p-value | OR (95% CI) | p-value | OR (95% CI) | |||||
rs61277615 | 5(0.0125) | 4(0.06061) | 2(0.03125) | 2(0.03125) | 0.008514 | 5.0968(1.3322 - 19.4998) | 0.2532 | 2.54849(0.4838 - 13.4239) | 0.2532 | 2.54849(0.4838 - 13.4239) |
rs73203482 | 3(0.0075) | 2(0.0303) | 2(0.03125) | 3(0.04688) | 0.09573 | 4.1354(0.6777 - 25.2338) | 0.08752 | 4.2688(0.6992 - 26.0617) | 0.009632 | 6.5082(1.2843 - 32.9812) |
rs804280 | 5(0.0125) | 0 | 5(0.07812) | 4(0.0625) | - | - | 0.0007886 | 6.6949(1.8812 - 23.8262) | 0.007083 | 5.2667(1.3755 - 20.1654) |
rs4841587 | 7(0.0175) | 2(0.0303) | 5(0.07812) | 2(0.03125) | 0.4838 | 1.7545(0.3565 - 8.6342) | 0.004553 | 4.7579(1.4622 - 15.4814) | 0.459 | 1.8111(0.3678 - 8.9182) |
rs4841588 | 8(0.02) | 1(0.01515) | 10(0.1562) | 4(0.0625) | 0.7909 | 0.7538(0.0927 - 6.1274) | 0.0000001597 | 9.0741(3.4321 - 23.9913) | 0.04671 | 3.2667(0.9542 - 11.1831) |