SNP | Genotype | Cases (N %) | Controls (N %) | Crude OR (95% CI) | Adjusted OR a(95% CI) | P value a | P-trend a | Call rate | HWE-test |
---|---|---|---|---|---|---|---|---|---|
rs2241766 | TT | 153 (47.4) | 374 (52.6) | 1 | 1 | Â | 0.137 | 96.91% | 0.462 |
TG | 141 (43.7) | 278 (39.0) | 1.24 (0.94-1.63) | 1.26 (0.95-1.66) | 0.109 | ||||
GG | 29 (9.0) | 59 (8.3) | 1.20 (0.74-1.95) | 1.24 (0.76-2.02) | 0.389 | ||||
TG + GG |  |  | 1.23 (0.95-1.60) | 1.25 (0.96-1.64) | 0.096 | ||||
rs822395 | AA | 226 (69.5) | 501 (71.7) | 1 | 1 | Â | 0.670 | 96.00% | 0.529 |
AC | 89 (27.4) | 179 (25.6) | 1.10 (0.82-1.49) | 1.09 (0.81-1.47) | 0.587 | ||||
CC | 10 (3.1) | 19 (2.7) | 1.17 (0.53-2.55) | 1.07 (0.48-2.35) | 0.870 | ||||
AC + CC |  |  | 1.11 (0.83-1.48) | 1.09 (0.81-1.45) | 0.582 | ||||
rs266729 | CC | 164 (49.0) | 378 (52.1) | 1 | 1 | Â | 0.219 | 99.63% | 0.054 |
CG | 152 (45.4) | 305 (42.1) | 1.15 (0.88-1.51) | 1.18 (0.90-1.54) | 0.233 | ||||
GG | 22 (5.7) | 42 (5.8) | 1.21 (0.70-2.09) | 1.23 (0.71-2.13) | 0.469 | ||||
CG + GG |  |  | 1.16 (0.89-1.50) | 1.18 (0.91-1.54) | 0.203 | ||||
rs1501299 | GG | 197 (60.6) | 420 (59.2) | 1 | 1 | Â | 0.512 | 96.81% | 0.306 |
TG | 110 (33.8) | 244 (34.5) | 0.96 (0.72-1.27) | 0.95 (0.71-1.26) | 0.708 | ||||
TT | 18 (5.5) | 44 (6.2) | 0.87 (0.49-1.55) | 0.83 (0.46-1.48) | 0.530 | ||||
TG + TT |  |  | 0.95 (0.72-1.24) | 0.92 (0.70-1.21) | 0.594 | ||||
rs12733285 | CC | 289 (85.5) | 614 (86.0) | 1 | 1 | Â | 0.848 | 98.59% | 0.106 |
CT | 47 (13.9) | 93 (13.0) | 1.07 (0.74-1.57) | 1.03 (0.71-1.52) | 0.846 | ||||
TT | 2 (0.6) | 7 (1.0) | 0.61 (0.13-2.94) | 0.55 (0.11-2.69) | 0.460 | ||||
CT + TT |  |  | 1.04 (0.70-1.53) | 1.00 (0.69-1.45) | 0.994 | ||||
rs1342387 | CC | 159 (48.0) | 289 (40.5) | 1 | 1 | Â | Â | Â | Â |
CT | 135 (40.8) | 312 (43.8) | 0.79 (0.59-1.04) | 0.80 (0.60-1.06) | 0.123 | Â | Â | Â | |
TT | 37 (11.2) | 112 (15.7) | 0.60 (0.39- 0.91) | 0.59 (0.38 -0.89) | 0.013 | 0.009 | 97.84% | 0.072 | |
CT + TT |  |  | 0.74 (0.57- 0.96) | 0.74 (0.57- 0.97) | 0.028 |  |  |  |