| Mean common carotid IMT (n = 1689) | Mean internal carotid IMT (n = 1687) | Mean B-score (n = 1759) | |||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
SNP | Age-and sex-adjusted | Fully adjusted | Age-and sex-adjusted | Fully adjusted | Age-and sex-adjusted | Fully adjusted | ||||||
 | β (se) | p-value | β (se) | p-value | β (se) | p-value | β (se) | p-value | β (se) | p-value | β (se) | p-value |
FOXO1 | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |
rs17446593 | -0.00046 (0.00052) | 0.3934 | -0.00047 (0.00052) | 0.3821 | 0.00041 (0.00057) | 0.5654 | 0.00053 (0.00056) | 0.4289 | 0.00391 (0.02081) | 0.7763 | 0.00648 (0.02066) | 0.6889 |
rs2721068 | -0.00089 (0.00045) | 0.0412 | -0.00106 (0.00045) | 0.0145 | -0.00049 (0.00049) | 0.2739 | -0.00055 (0.00048) | 0.2224 | -0.01029 (0.01803) | 0.6473 | -0.01329 (0.01786) | 0.5229 |
rs17446614 | -0.00118 (0.00054) | 0.0272 | -0.00125 (0.00053) | 0.0180 | -0.00032 (0.00058) | 0.4625 | -0.00027 (0.00058) | 0.5278 | -0.00860 (0.02131) | 0.7509 | -0.00725 (0.02118) | 0.7789 |
rs10507486 | -0.00168 (0.00042) | 0.0007 | -0.00184 (0.00047) | 0.0002 | -0.00083 (0.00052) | 0.1080 | -0.00079 (0.00052) | 0.1278 | -0.02940 (0.01907) | 0.1178 | -0.03007 (0.01898) | 0.1007 |
rs2297627 | -0.00144 (0.00042) | 0.0008 | -0.00158 (0.00042) | 0.0002 | -0.00100 (0.00046) | 0.0333 | -0.00104 (0.00045) | 0.0253 | -0.03310 (0.01681) | 0.0516 | -0.03620 (0.01664) | 0.0301 |
SIRT1 | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |
rs3740051 | 0.00048 (0.00082) | 0.5530 | 0.00053 (0.00081) | 0.5012 | 0.00044 (0.00088) | 0.7644 | 0.00068 (0.00088) | 0.5590 | 0.00096 (0.03260) | 0.9972 | 0.00816 (0.03250) | 0.8322 |
rs2236319 | 0.00033 (0.00082) | 0.7001 | 0.00039 (0.00081) | 0.6382 | 0.00016 (0.00088) | 0.9579 | 0.00039 (0.00088) | 0.7410 | -0.00578 (0.03272) | 0.8706 | 0.00484 (0.03254) | 0.8668 |
rs12413112 | 0.00177 (0.00061) | 0.0157 | 0.00206 (0.00061) | 0.0037 | 0.00100 (0.00066) | 0.1375 | 0.00108 (0.00066) | 0.1064 | 0.05019 (0.02423) | 0.0847 | 0.04818 (0.02411) | 0.0989 |
rs10823108 | 0.00031 (0.00081) | 0.6926 | 0.00038 (0.00080) | 0.6102 | -0.00002 (0.00087) | 0.9096 | 0.00024 (0.00087) | 0.8477 | -0.01326 (0.03240) | 0.6779 | -0.00217 (0.03222) | 0.9476 |
rs2273773 | 0.00052 (0.00081) | 0.5360 | 0.00059 (0.00081) | 0.4716 | 0.00023 (0.00088) | 0.9143 | 0.00045 (0.00088) | 0.7025 | -0.00549 (0.03257) | 0.8698 | 0.00502 (0.03239) | 0.8692 |
rs1467568 | 0.00034 (0.00042) | 0.5594 | 0.00045 (0.00041) | 0.3747 | 0.00063 (0.00045) | 0.2329 | 0.00072 (0.00045) | 0.1563 | 0.03433 (0.01659) | 0.0775 | 0.03577 (0.01645) | 0.0643 |