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Table 2 Correlation between CYP1B1 mutations and Severity of PCG in native (23) and non-native (11) Saudi

From: CYP1B1 mutations in patients with primary congenital glaucoma from Saudi Arabia

 

Severity

Mild

Moderate

Severe

None

G61E

R469W

E229K

None

G61E

R469W

E229K

None

G61E

R469W

E229K

No. of Native Saudi (%)

1 (4.4)

6 (26.1)

2 (8.7)

0 (0)

0 (0)

5 (21.7)

2 (8.7)

0 (0)

1 (4.4)

4 (17.4)

2 (8.7)

0 (0)

No. of Non-Native Saudi (%)

2 (18.2)

1 (9.1)

0 (0)

0 (0)

2 (19.2)

1 (9.1)

1 (9.1)

1 (9.1)

1 (9.1)

1 (9.1)

1 (9.1)

0 (0)

Total (%)

3 (8.8)

7 (20.6)

2 (5.9)

0 (0)

2 (5.9)

6 (17.7)

3 (8.8)

1 (2.9)

2 (5.9)

5 (15.8)

3 (8.8)

0 (0)

  1. [9] Mild: (IOP < 25 mmHg, Corneal diameter < 13 mm, Clear cornea).
  2. Moderate: (IOP = 25-35 mmHg, corneal diameter = 13-14.5 mm, hazy cornea).
  3. Severe: (IOP > 35 mmHg, corneal diameter > 14.5 mm, cloudy cornea).