From: Alternative splicing in osteoclasts and Paget’s disease of bone
Description | Ψ values (long/long +short) (+/− SD) | all PDBvsHD | ||||
---|---|---|---|---|---|---|
Gene symbol | Protein name | AS event description | Alternative products* | All PDB | All HD | p-value** |
n=19 | n=16 | |||||
LGALS8 | lectin, galactoside-binding, soluble, 8 Galectin-8 | cassette exon, 142 nt, coding region, in frame | - isoform 1: 317 aa, 36 kDa (short) | 0.08 (0.04) | 0.14 (0.04) | 0.00001 |
- isoform 2: 359 aa, 40.5 kDa (long) | ||||||
USP4 | ubiquitin specific peptidase 4 | cassette exon, 141 nt, coding region, in frame | - isoform 1: 963 aa, 109 kDa (long) | 0.20 (0.04) | 0.27 (0.06) | 0.0002 |
(proto-oncogene) | - isoform 2: 916 aa, 104 kDa (short) | |||||
CASC4 | cancer susceptibility candidate 4 | cassette exon, 168 nt, coding region, in frame | - isoform 1: 436 aa, 49 kDa (long) | 0.21 (0.06) | 0.29 (0.06) | 0.001 |
- isoform 2: 380 aa, 43 kDa (short) | ||||||
- isoform 3: 177 aa, 21 kDa | ||||||
RHOT1 | ras homolog family member T1 | cassette exon, 96 nt, coding region, in frame | - isoform 1: 618 aa, 71 kDa | 0.16 (0.04) | 0.23 (0.08) | 0.001 |
- isoform 2: 659 aa, 75 kDa (short) | ||||||
- isoform 3: 691 aa, 80 kDa (long) | ||||||
MIRO1 | - isoform 4: 580 aa, 66 kDa | |||||
PIDD | p53-induced death domain protein | 3′ AS site, 51 nt, coding region, in frame | - isoform 1 910 aa, 100 kDa (long) | 0.63 (0.06) | 0.58 (0.05) | 0.01 |
- isoform 2: 893 aa, 98 kD (short) | ||||||
- isoform 3: 753 aa, 83 kDa | ||||||
LRDD | - isoform 4: 597 aa, 67 kDa | |||||
TBC1D25 | TBC1 domain family, member 25 | cassette exon, 155 nt, 5′ untranslated region | - isoform 1: 688 aa, 76 kDa (long) | 0.63 (0.05) | 0.68 (0.06) | 0.03 |
OATL1 | - isoform 2: 100 aa, 10 kDa (short) |