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Table 1 Minimal adequate genetic model of G6PD activity

From: Genetic determinants of glucose-6-phosphate dehydrogenase activity in Kenya

SNP

Allelic ES (95% CI)

% change

c.202

-0.198 (-0.213 - -0.183)

-37.9

rs2230037 (H+)

+0.022 (+0.011 - +0.034)

4.3

c.376 (H-)

-0.017 (-0.030 - -0.005)

-3.3

  1. A linear model containing both c.202G>A as well as SNPs tagging the H+ (rs2230037) and H- (c.376A>G) haplotypes explained significantly more variance than a model containing c.202G>A alone (P <0.001), and could not be improved via the inclusion of additional SNPs.
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BMC Medical Genetics

ISSN: 1471-2350

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