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Table 4 Results of haplotype association analysis for type 2 diabetes in interaction effect models (n = 1,968).

From: Association between variations in the TLR4gene and incident type 2 diabetes is modified by the ratio of total cholesterol to HDL-cholesterol

  Men Women
  HR [95% CI] p-value HR [95% CI] p-value
TC/HDL-C 1.02 [0.90; 1.15] 0.74 1.95 [1.55; 2.45] 1.2 × 10-8
H2 0.77 [0.36, 1.65] 0.5 3.11 [1.07; 9.00] 0.04
H3 1.04 [0.55; 1.96] 0.89 4.41 [1.37; 14.21] 0.01
H4 0.29 [0.08; 1.02] 0.05 4.01 [0.99; 16.17] 0.05
H5 0.11 [0.03; 0.45] 1.9 × 10-3 1.47 [0.34; 6.40] 0.61
H6 0.45 [0.11; 1.73] 0.24 0.29 [0.01; 6.73] 0.44
H7 0.05 [0.00; 0.52] 0.01 0.41 [0.02; 10.33] 0.59
TC/HDL-C × H2 1.08 [0.95; 1,24] 0.22 0.76 [0.61; 0.96] 0.02
TC/HDL-C × H3 1.01 [0.92; 1.10] 0.9 0.70 [0.54; 0.91] 0.01
TC/HDL-C × H4 1.28 [1.03; 1.58] 0.02 0.68 [0.51; 0.89] 0.01
TC/HDL-C × H5 1.51 [1.23; 1.87] 1.1 × 10-4 0.95 [0.70; 1.29] 0.74
TC/HDL-C × H6 1.14 [0.95; 1.37] 0.15 1.17 [0.65; 2.08] 0.61
TC/HDL-C × H7 1.63 [1.26; 2.12] 2.1 × 10-4 1.15 [0.64; 2.07] 0.64