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Table 2 Description of TLR4 variants genotyped (n = 1,968).

From: Association between variations in the TLR4gene and incident type 2 diabetes is modified by the ratio of total cholesterol to HDL-cholesterol

SNP number

dbSNP identifier

Exchange

Genotype frequenciesa

Gene location

  

(1 > 2)

11

12

22

 

1

rs2770150

T > C

52.6

40.1

7.3

5'Upstream

2

rs6478317

A > G

46.5

42.7

10.8

5'Upstream

3

rs1927911

C > T

57.6

35.7

6.7

Intronic

4

rs2149356

C > A

47.7

42.2

10.1

Intronic, TFBS

5

rs4986791

C > T

88.1

11.6

0.3

Ile399Thr, HMCS

6

rs7873784

G > C

74.2

23.4

2.4

3'Untranslated region

7

rs1927906

A > G

81.3

18

0.8

3'Flanking

  1. aweighted due to the sampling schene; TFBS: Transcription factor binding site; HMCS: human-mouse conserved segments